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Wayne State University School of Medicine
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Clinical Research


OVERVIEW

PEDIATRIC DISORDERS

ADHD Children "Assessing Developmental Trajectories of the Brain Biochemistry in ADHD at 3 Tesla" (PI: J. A. Stanley; NIMH 5R01 MH065420)

Attention Deficit Hyperactivity Disorder (ADHD) is a serious public health problem that affects between 3 to 9% of children and accounts for between 30 to 40% of child referrals to mental health services. While the cause of this illness remains poorly understood, ADHD is increasingly seen as a neurodevelopmental disorder. This work promises to identify where in the brain and at what age certain alterations occur in children and adolescents with ADHD, and this information of changes with age can then potentially be used as a predictor of treatment outcome.

Research Volunteers Needed ... (313) 577-6279

 

Prenatal Alcohol Exposure"Neurodevelopmental Trajectories in Children Exposed Prenatally to Alcohol: A Multi-Voxel 31P and 1H Spectroscopy Study at 4 Tesla" (PI: J. A. Stanley and J. Hannigan)

Obsessive Compulsive Disorder"Research in Pediatric OCD" (PI: D. Rosenberg)

Obsessive Compulsive Disorder"Brain chemistry and genetics in pediatric OCD" (PI: D. Rosenberg)

 

SCHIZOPHRENIA and BIPOLAR DISORDERS

Adolescents at Risk"Neuroimaging studies in children at risk for Bipolar disorders and Schizophrenia." (PI: V. Diwadkar)

Adolescents at Risk"fMRI studies in adolescents at risk for schizophrenia. (PI: V. Diwadkar)"

Adolescents at Risk"Precursors of schizophrenia or mood disorder: fMRI studies in at-risk adolescents" (PI: V. Diwadkar)

Schizophrenia"Learning, Altered Plasticity & Glutamate in Early Schizophrenia: fMRI/MRS Studies" (PI: V. Diwadkar)

 

SUBSTANCE DEPENDENT DISORDERS

Opioid Dependent"Brain chemistry in opioid dependent volunteers and controls using MR Spectroscopy" (PI: M. Greenwald)

 

OTHER DISORDERS

Post-Traumatic Stress Disorder"Prefrontal Cortical Function in PTSD: A Proton MRS Study" (PI: B. Martis, VA at U. of Michigan)